Analysis of Risk Factors for Recurrence and Metastasis of Differentiated Thyroid Carcinoma After Endoscopic Surgery
Objective To analyze the risk factors of recurrence and metastasis of differentiated thyroid carcinoma(DTC)after endoscopic surgery.Methods A total of 112 patients with DTC who underwent endoscopic surgery in Wanzai County People's Hospital from December 2019 to December 2021 were enrolled in the study.As of September 2023,a total of 32 patients with postoperative recurrence and metastasis were set as recurrence and metastasis group,and a total of 80 patients without recurrence and metastasis were set as non-recurrence and metastasis group.The baseline data were collected,and the risk factors of recurrence and metastasis of DTC after endoscopic surgery were analyzed by univariate and multivariate Logistic analysis.Results There were statistically significant differences in age,pathological type,tumor diameter,clinical stage,preoperative lymph node metastasis,number of lesions,and postoperative oral thyroxine between the recurrence and metastasis group and the non-recurrence and metastasis group(P<0.05),while the proportion of patients with age≥45 years old,tumor type FTC,tumor diameter≥5 cm,clinical stage Ⅲ-Ⅳ,preoperative lymph node metastasis,multiple lesions,and postoperative non-oral thyroxine in the recurrence and metastasis group was higher than that in the non-recurrence and metastasis group.Logistic regression analysis showed that age≥45 years old(OR:2.932,95%CI:1.208-4.217),tumor diameter≥5 cm(OR:2.653,95%CI:1.054-3.435),clinical stage Ⅲ-Ⅳ(OR:2.134,95%CI:1.129-3.741),preoperative lymph node metastasis(OR:2.241,95%CI:1.632-4.063),multiple lesions(OR:2.173,95%CI:1.339-3.648)were independent risk factors for recurrence and metastasis in DTC patients after endoscopic surgery(P<0.05).Conclusion Recurrence and metastasis of DTC patients after endoscopic surgery are closely related to age,tumor diameter,clinical stage,preoperative lymph node metastasis and multiple lesions.
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