Study on Magnetic Resonance T2 Mapping and mDixon Quant Technology in Lumbar Disc Degeneration
Objective To explore the application value of magnetic resonance mDixon Quant and T2 mapping quantitative techniques in evaluating paravertebral muscle group and intervertebral disc degeneration in chronic low back pain.Methods A total of 54 patients with chronic low back pain who were treated in our hospital from July 2021 to August 2022 were collected as the low back pain group,and 50 healthy volunteers were selected as the control group.Both groups were scanned by sagittal T2 mapping,axial mDixon Quant sequence and conventional lumbar sequence.The fat fraction(FF)of psoas major(PM)and erector spinae(ES)and the T2 values of anterior annulus fibrosus(AAF),nucleus pulposus(NP)and posterior annulus fibrosus(PAF)were measured.The differences of PM,ES fat fraction and intervertebral disc AAF,NP,PAF T2 values between the low back pain group and the control group were compared,and the correlation between the fat fraction of paraspinal muscle and intervertebral disc degeneration in the low back pain group was analyzed.Results There was significant difference in T2 value of NP between the low back pain group and the control group(P<0.05),but there were no significant differences in the T2 values of PM,ES fat fraction,intervertebral disc AAF and PAF between the two groups(P>0.05).There was a moderate positive correlation between the fat fraction of erector spinae and intervertebral disc degeneration in the low back pain group(r=0.570,P<0.05).Conclusion There is a moderate correlation between the fat fraction of erector spinae muscle and lumbar disc degeneration in patients with chronic low back pain,especially in the nucleus pulposus area.Therefore,the fat fraction of paraspinal muscle can be used as one of the biomarkers for evaluating intervertebral disc degeneration.