Effect of Traditional Chinese Medicine Bath Assisted Intermittent Blue Light Irradiation on Neonatal Hyperbilirubinemia and its Effect on Immune Function and Bilirubin Level
Objective To study the effect of traditional Chinese medicine bath assisted intermittent blue light irradiation on neonatal hyperbilirubinemia(NHB)and its effect on immune function and bilirubin level.Methods From July 2019 to July 2023,58 children with NHB received by Ganzhou Nankang Maternal and Child Health Hospital were selected as the research objects.They were divided into control group(29 children)and observation group(29 children)by random number table method.The control group was treated with intermittent blue light irradiation,and the observation group was treated with traditional Chinese medicine bath on the basis of the control group.The serum bilirubin levels[total bilirubin(TBIL),indirect bilirubin(IBIL)],bilirubin decline,defecation frequency,sleep duration,immune function(peripheral blood CD4+,CD8+,CD4+/CD8+),meconium yellowing time and jaundice regression time were compared between the two groups.Results The levels of TBIL and IBIL in the two groups after treatment were lower than those before treatment,and the levels of TBIL and IBIL in the observation group after treatment were lower than those in the control group(P<0.05).The average daily decrease of TBIL and IBIL in the observation group was greater than that in the control group(P<0.05).After treatment,the defecation frequency and sleep duration of the two groups were higher than those before treatment,and the defecation frequency and sleep duration of the observation group were longer than those of the control group(P<0.05).After treatment,CD4+and CD4+/CD8+in the two groups were higher than those before treatment,and CD4+and CD4+/CD8+in the observation group were higher than those in the control group(P<0.05).The time of meconium turning yellow and jaundice regression in the observation group were shorter than those in the control group(P<0.05).Conclusion Traditional Chinese medicine bath assisted intermittent blue light irradiation therapy can accelerate the decrease of bilirubin in children with NHB,increase the frequency of defecation,prolong the sleep time,help to improve the immune function of children,and shorten the time of jaundice regression.
Neonatal hyperbilirubinemiaIntermittent blue light irradiationTraditional Chinese medicine bathImmunefunctionSerum bilirubin
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