A Comparative Study of Torasemide and Furosemide on the Risk of Hypokalemia Caused by Diuresis in Patients with Cirrhotic Ascites
Objective To compare the risk of diuretic-induced hypokalemia between torasemide and furosemide in patients with cirrhotic ascites. Methods A total of 66 patients with cirrhotic ascites admitted to Ruijin People's Hospital from October 2021 to September 2023 were selected as the research objects. According to the random number table method,they were divided into furosemide treatment group and torasemide treatment group,with 33 patients in each group. The furosemide treatment group was treated with furosemide,and the torasemide treatment group was treated with torasemide. The diuretic effect (body weight,urine volume),serum electrolyte (serum potassium,serum sodium) and the incidence of adverse reactions (hepatomegaly,infection,peritonitis,gastrointestinal bleeding,hepatic encephalopathy) were compared between the two groups. Results The diuretic effect of torasemide treatment group was better than that of furosemide treatment group (P<0.05). After 3 days of treatment,the levels of serum potassium and sodium in the torasemide treatment group were higher than those in the furosemide treatment group (P<0.05). The incidence of adverse reactions in the torasemide treatment group was lower than that in the furosemide treatment group (P<0.05).Conclusion Torasemide can significantly improve serum potassium and serum sodium in patients with cirrhotic ascites,promote urine excretion,and has higher therapeutic effect and safety. It is worthy of application.
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