Clinical Study of Nasal Negative Pressure Replacement Combined with Mechanical Assisted Expectoration Oxygen Atomization in the Treatment of Pneumonia in Children
Objective To study the clinical efficacy of nasal negative pressure replacement combined with mechanical assisted sputum oxygen atomization in the treatment of children with pneumonia.Methods A total of 72 children with pneumonia diagnosed and treated in our hospital from March 2022 to September 2023 were selected as the research objects. They were divided into control group and study group by random number table method,with 36 children in each group. The control group was treated with mechanical assisted expectoration oxygen atomization,and the study group was treated with nasal negative pressure replacement on the basis of the control group. The treatment effect,disappearance time of clinical symptoms (cough,body temperature,lung rale),blood gas indexes[oxygen partial pressure (PaO2),carbon dioxide partial pressure (PaCO2),pH],inflammatory factors[C-reactive protein (CRP),procalcitonin (PCT),interleukin-6 (IL-6)]were compared between the two groups. Results The total effective rate of treatment in the study group (94.44％) was higher than that in the control group (83.33％) (P<0.05). The time of cough disappearance,body temperature recovery and lung rale disappearance in the study group were shorter than those in the control group (P<0.05). After treatment,PaO2 and pH in the two groups were higher than those before treatment,PaCO2 was lower than that before treatment,and PaO2 and pH in the study group were higher than those in the control group,PaCO2 was lower than that in the control group (P<0.05). After treatment,the levels of CRP,PCT and IL-6 in the two groups were lower than those before treatment,and those in the study group were lower than those in the control group ( P<0.05).Conclusion The clinical effect of nasal negative pressure replacement combined with mechanical assisted expectoration and oxygen atomization in the treatment of pediatric pneumonia is ideal,which can improve the total effective rate,improve the blood gas index,reduce the inflammatory reaction,and is conducive to the rapid disappearance of clinical symptoms in children. It is worthy of clinical application.
万方数据
维普
