Analysis of Bacterial Culture and Drug Sensitivity Results of Amniotic Fluid and Fetal Membrane in Cesarean Section Women with Premature Rupture of Membranes and Amniotic Fluid Turbidity
Objective To analyze the results of bacterial culture and drug sensitivity of amniotic fluid and fetal membranes in cesarean section women with premature rupture of membranes and amniotic fluid turbidity.Methods A total of 102 amniotic fluid and fetal membrane specimens (54 cases of premature rupture of membranes and 48 cases of amniotic fluid turbidity ) collected from January 2022 to December 2023 in Yudu Maternal and Child Health Hospital were selected for bacterial culture and drug sensitivity test. The detection rate of pathogenic bacteria in amniotic fluid and fetal membrane specimens was counted,and the drug resistance of main pathogenic bacteria to different antibiotics was analyzed. Results Among the 102 samples,67 strains of Gram-negative bacteria were detected,with a detection rate of 65.69％. The main pathogenic bacteria were Escherichia coli,accounting for 51.96％ (53/102) of the total samples. A total of 35 strains of Gram-positive bacteria were detected,with a detection rate of 34.31％. The main pathogenic bacteria were Enterococcus faecalis,accounting for 20.59％ (21/102) of the total sample. The results of drug sensitivity showed that the resistance rate of Escherichia coli to ampicillin was the highest (86.79％),followed by cefazolin (67.92％). Escherichia coli was sensitive to other antibiotics,and the sensitivity rate was more than 65％. At the same time,the sensitivity of Enterococcus faecalis to ampicillin and penicillin was the highest,reaching 95.24％,and it was more resistant to other antibiotics,and the resistance rate was higher than 50％. Conclusion Gram-negative bacteria and Gram-positive bacteria are common pathogens of premature rupture of membranes. The former accounts for a large proportion. The main pathogen is Escherichia coli,which has high resistance to ampicillin and cefazolin,and is sensitive to other drugs. The main pathogen of the latter is Enterococcus faecalis,which is most sensitive to ampicillin and penicillin,and has high drug resistance in other drugs.
Premature rupture of membranesAmniotic fluid turbidityCesarean sectionAmniotic fluid and fetal membrane specimensBacterial cultureDrug sensitivity test
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