Clinical Value of Contrast-enhanced Ultrasound Combined with Enhanced CT in the Early Differential Diagnosis of Focal Liver Nodules and Small Hepatocellular Carcinoma
Objective To analyze the clinical value of contrast-enhanced ultrasound combined with enhanced CT in the early differential diagnosis of focal liver nodules and small hepatocellular carcinoma.Methods A total of 60 patients with suspected focal hepatic nodules and small hepatocellular carcinoma admitted to Xingan County People's Hospital from January 2020 to August 2023 were selected as the research objects. According to the random number table method,all patients were divided into control group and study group,with 30 patients in each group. The control group was treated with enhanced CT,and the study group was treated with liver contrast-enhanced ultrasound on the basis of the control group. The echo of liver parenchyma,lesion changes (high enhancement,equal enhancement,low enhancement),enhancement mode (fast in fast out,fast in equal out,fast in slow out,equal in slow out) and the number of true and false positive cases were compared between the two groups at different stages (arterial phase,portal phase,delayed phase). The accuracy,sensitivity and specificity of the two groups were compared. Results The proportion of equal enhancement in the arterial phase of the study group was lower than that of the control group,while the proportion of high enhancement was higher than that of the control group;the proportion of low enhancement in portal venous phase and delayed phase in the study group was higher than that in the control group,while the proportion of equal enhancement was lower than that in the control group (P<0.05). The enhancement mode of the study group was better than that of the control group,and the sensitivity,specificity and accuracy were higher than those of the control group (P<0.05).Conclusion Contrast-enhanced ultrasound combined with enhanced CT is of great value in the early clinical differential diagnosis of focal liver nodules and small hepatocellular carcinoma. It has high specificity,sensitivity and accuracy,and is worthy of clinical application.
Contrast-enhanced ultrasoundEnhanced CTFocal nodules of liverSmall hepatocellular carcinomaEarly stageDifferential diagnosis