Application of Combined Detection of White Blood Cell Count,C-reactive Protein and Interleukin-6 in the Diagnosis of Pediatric Infectious Diseases
Objective To investigate the clinical value of combined detection of C-reactive protein (CRP),interleukin-6 (IL-6) and white blood cell count (WBC) in the early diagnosis of pediatric infectious diseases.Methods A total of 230 patients with pediatric infectious diseases admitted to the laboratory department of Shanggao County Hospital of Traditional Chinese Medicine from January 2020 to January 2022 were selected as the research objects. According to the etiological type,they were divided into viral infection group (n=88) and bacterial infection group (n=142). Another 50 healthy subjects who underwent physical examination during the same period were selected as the control group. CRP,IL-6 and WBC were examined in all three groups. The diagnostic value of single detection and combined detection of the above three indicators for pediatric infectious diseases was compared.Results The levels and positive rates of CRP,IL-6 and WBC in the bacterial infection group were higher than those in the control group and the viral infection group,and the differences were statistically significant (P<0.05). The diagnostic specificity,sensitivity,positive predictive value,negative predictive value and diagnostic accuracy of CRP,IL-6 and WBC alone were lower than those of combined detection,and the differences were statistically significant (P<0.05).Conclusion Compared with single detection of CRP,IL-6 and WBC,combined detection can improve the detection and diagnosis accuracy of pediatric infectious diseases,which is worthy of clinical application.
万方数据
维普
