Clinical Effect and Safety Analysis of β2 Receptor Agonist Combined with Antibiotics in Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Objective To observe the clinical effect and safety of β2 receptor agonist combined with antibiotics in acute exacerbation of chronic obstructive pulmonary disease.Methods During January,2022 and March,2023,80 patients with acute exacerbation of chronic obstructive pulmonary disease admitted to our hospital were collected,and grouped by random number table method,while 40 patients were enrolled in the routine group and 40 patients were enrolled in the research group.Antibiotics was used for treatment in the routine group,while the research group was added β2 receptor agonist on the basis of the method which was carry out in the routine group.Results In comparison with the routine group,the research group was observed to have a higher total effective rate(P＜0.05).Compared with the patients in the routine group after the treatment,6-minute walking distance,dyspnea grading scores,and FEV1,FEV1/FVC,PaO2,PaCO2 level in the research group were significantly superior to the routine group(P＜0.05).The incidence of adverse reactions in the research group was 7.50%,which was compared with 10.00%in the routine group,the difference was not statistically significant(P＞0.05).Conclusion β2 receptor agonist combined with antibiotics has a definite effect in the acute exacerbation of chronic obstructive pulmonary disease,which can reduce the dyspnea score of patients,improve the treatment efficiency,increase the 6-minute walking distance,improve lung function and blood gas index,and do not increase the incidence of clinical adverse reactions.It is worthy of clinical application.
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