Clinical Efficacy of Amoxicillin and Clavulanate Potassium Granules in the Treatment of Acute Gastroenteritis
Objective To observe the clinical efficacy of amoxicillin and clavulanate potassium granules in the treatment of acute gastroenteritis.Methods Using the random number table method,62 acute gastroenteritis patients who diagnosed and treated in our hospital from January 2021 to March 2023 were selected as the research objects and divided into control group(n=31)and observation group(n=31).In the control group,patients were treated with azithromycin,while in the observation group,patients were treated with amoxicillin and clavulanate potassium granules.The clinical efficacy,disappearance time of clinical symptoms(abdominal pain,diarrhea,vomiting),inflammatory index factors[C-reactive protein(CRP),white blood cell count(WBC)],gastrointestinal function grading and incidence of adverse reactions were compared between the two groups.Results The observation group(93.55%)had higher the total effective rate of treatment than that in the control group(80.65%)(P＜0.05).Compared with the control group,the observation group had lower disappearance time of abdominal pain,diarrhea and vomiting(P＜0.05).Compared with before treatment,CRP and WBC in the two groups were decreased after treatment,and compared with the control group,the observation group had lower CRP and WBC levels(P＜0.05).Compared with the control group,the observation group had higher the proportion of gastrointestinal function AGI grade Ⅰ,and lower the proportion of AGI grade Ⅱ and AGI grade Ⅲ(P＜0.05).The observation group(6.45%)had lower the incidence of adverse reactions than that in the control group(19.35%)(P＜0.05).Conclusion Amoxicillin and clavulanate potassium granules have an ideal effect in the treatment of acute gastroenteritis,which can shorten the disappearance time of clinical symptoms,reduce the level of inflammatory factors,promote the recovery of gastrointestinal function,and reduce the incidence of adverse reactions.
Amoxicillin and clavulanate potassium granulesAcute gastroenteritisC-reactive proteinGastrointestinal function classification
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