Diagnostic Value of C-reactive Proteinand SAA in Micro-inflammatory State of Uremic Dialysis Patients
Objective To study the diagnostic value of C-reactive protein(CRP)and serum amyloid A(SAA)for microinflammatory state in uremic dialysis patients.Methods From January 2022 to November 2023,60 patients with uremia who underwent dialysis treatment in Shangrao Hospital of Traditional Chinese Medicine were selected as the research objects.34 patients with micro-inflammatory state were set as micro-inflammatory group,and 26 patients with non-inflammatory state were set as non-inflammatory group.CRP and SAA were detected in all patients.The levels of CRP and SAA in uremic patients before and after dialysis were compared.The levels of CRP and SAA in the micro-inflammatory group and the non-inflammatory group were compared.The receiver operating characteristic curve(ROC)was drawn to analyze the diagnostic value of CRP and SAA in the micro-inflammatory state of uremic dialysis patients.Results The levels of CRP and SAA in uremic patients after dialysis were higher than those before dialysis(P＜0.05).The levels of CRP and SAA in the micro-inflammation group were higher than those in the non-inflammation group(P＜0.05).ROC curve showed that CRP and SAA had definite diagnostic value for microinflammatory state in uremic dialysis patients(AUC＞0.5,P＜0.05),and the AUC value of combined detection was higher than that of single detection(P＜0.05).Conclusion CRP and SAA have definite diagnostic value for micro-inflammatory state in uremic dialysis patients,and the combined detection of CRP and SAA has higher diagnostic efficiency.
HemodialysisMicro-inflammatory stateC-reactive proteinSerum amyloid protein A
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