Effects of Hemodialysis Combined with Hemoperfusion on Serum Calcium and Phosphorus,Blood Lipid and Renal Function Indexes in Patients with Chronic Kidney Disease
Objective To study the effect of hemodialysis(HD)combined with hemoperfusion(HP)on serum calcium,phosphorus,blood lipid and renal function in patients with chronic kidney disease.Methods Using the random number table method,totally 68 patients with chronic kidney disease admitted to the Department of Nephrology,Wannian County People's Hospital from July 2021 to October 2023 were divided into control group(34 patient)and observation group(34 patient).In the control group,patients were treated with HP,while in the observation group,patient were treated with HD combined with HP.The serum calcium and phosphorus levels,inflammatory indexes[C-reactive protein(CRP),interleukin(IL-6)],blood lipid levels[triglyceride(TG),total cholesterol(TC)],renal function indexes[serum creatinine(Scr),serum urea nitrogen(BUN)]were compared between the two groups.Results Compared with before treatment,the serum calcium content,Scr and BUN levels were higher,and the phosphorus content,CRP,IL-6,TG and TC levels were lower in the two groups after treatment,while compared with the control group,the serum calcium content was higher,and the phosphorus content,CRP,IL-6,TG,TC,Scr and BUN were lower in the observation group(P<0.05).Conclusion HD combined with HP can correct the balance of calcium and phosphorus metabolism in patients with chronic kidney disease,down-regulate their inflammatory indicators and blood lipid levels,and alleviate renal function damage.
HemodialysisHemoperfusionChronic kidney diseaseRenal functionSerum calcium and phosphorus contentBlood lipid levels
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