Research progress of SVF-gel in the treatment of diabetic wound
With the increasing incidence of diabetes,the refractory wound caused by chronic persistent hyperglycemia has been troubling the diabetic patients for a long time.Adipose Extracellular Matrix/Stromal Vascular Fraction Gel(SVF-gel)contains highly concentrated extracellular matrix and stromal vascular fraction(SVF),which not only provides the optimal microenvironment for the function of cells and cytokines,but also promotes wound angiogenesis,inhibit inflammatory response and stimulates epithelial cell proliferation and differentiation,and ultimately achieve the purpose of repairing refractory wounds.This article reviews the preparation,components,mechanism and application of SVF-gelin the treatment of diabetic wounds.
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