Construction and application of blood glucose regulation scheme for postoperative liver transplant patients
Objective To establish the blood glucose regulation scheme for postoperative liver transplant patients and evalu-ate its application effect.Methods The before-and-after control study was used.Fifty patients who underwent liver transplantation from July to December 2022 in Eastern Theater General Hospital were selected as the experimental group,and 50 patients who under-went liver transplantation from January to June 2022 were selected as the control group.The baseline data of the two groups were con-sistent.The experimental group adopted the blood glucose regulation scheme for liver transplantation patients after surgery,which was constructed based on evidence-based and Delphi expert consultation method.The blood glucose range,remeasured blood glucose val-ue,changes from the previous monitoring value,insulin adjustment scheme and monitoring frequency were explained in detail.The con-trol group received routine blood glucose regulation.The fluctuation amplitude of blood glucose,frequency of blood glucose monitoring,dosage of insulin,time required for blood glucose regulation to reach the target range,total time to stabilize within the target range,and in-cidence of adverse events of hypoglycemia were compared between the two groups.Results Within 48h of intervention,the blood glu-cose fluctuation range of the experimental group was(8.77±3.64)mmol/L,the dosage of insulin was(72.82±55.19)U,the time re-quired for hyperglycemia regulation to reach the target range was(660.80±335.45)min,and the total time for stable within the target range was(1939.20±426.36)min.The control group was[(11.38±5.03)mmol/L,(98.84±66.82)U,(871.40±459.29)min,(1611.20±530.44)min],respectively,and the differences were statistically significant(P<0.05).No hypoglycemia occurred in the experimental group 48 h after surgery,while 8 cases of hypoglycemia occurred in the control group,with statistical significance(P<0.05).There was no significant difference in the frequency of blood glucose moni-toring between the two groups within 48 h after operation(P>0.05).Conclusion The blood glucose regulation scheme of liver trans-plantation patients is accurate,feasible and safe,which can improve the blood glucose regulation effect of liver transplantation patients and promote the rapid recovery of patients after surgery.
critically ill patientsliver transplantationblood glucose managementblood glucose control
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