人工细胞在疾病治疗应用中的研究进展
Research progress in the application of artificial cells in the treatment of diseases
蒋文韬 1高政 1周敏1
作者信息
- 1. 210008 南京,南京大学医学院附属鼓楼医院血管外科
- 折叠
摘要
人工细胞作为研究人员在模仿自然细胞的基础上构建的仿生系统,过去几十年来在构建方面取得了巨大进步.向不同材料构成的人工细胞赋予跨膜运输、环境响应等各种功能,为其在医学领域的应用奠定了基础.文章主要对人工细胞在疾病治疗应用中的研究,包括作为载药系统、代替天然细胞功能、封装天然细胞、用于酶和基因治疗以及免疫疗法等进行综述.
Abstract
Artificial cells,as a bionic system built by researchers on the basis of imitating natural cells,have made great prog-ress in construction over the past few decades.The artificial cells composed of different materials are endowed with various functions such as transmembrane transport and environmental response,which lays a foundation for their application in the medical field.This ar-ticle mainly reviews the application of artificial cells in the treatment of diseases,including as a drug delivery system,replacing the function of natural cells,encapsulating natural cells,used in enzyme and gene therapy and immunotherapy.
关键词
人工细胞/疾病治疗/载药系统/替代天然细胞Key words
artificial cells/disease treatment/drug delivery system/natural cell substitute引用本文复制引用
基金项目
国家自然科学基金(82272098)
江苏省研究生科研创新计划项目(KYCX23_0191)
出版年
2024
NETL
NSTL
万方数据