Objective To investigate the application value of plain CT and dynamic CT enhancement in differentiating angiomy-olipomas with minimal fat(AMLmf)and three common pathological types of renal carcinoma.Methods 83 cases of solid renal mass were retrospectively analyzed,among which 15 were pathologically confirmed as AMLmf,15 as PRCC of the kidney,27 as CCRCC of the kidney,and 26 as ChRCC of the kidney.All 83 patients underwent CT plain scan and phase Ⅲ dy-namic enhancement examination before surgery.The CT value of plain scan and dynamic enhanced CT in solid mass area were measured respectively,and then,the CT value differences between plain scan and each stage of enhanced CT were calculated.One-way ANOVA was performed for comparison of CT differences between the two groups at each stage.The uniformity of the density of plain scan,uniformity of enhanced density,cystic lesions,star and scar,splitting sign and calcification were ob-served in the four groups,and then,analyzed by x2 test or Fisher's exact probability method.Results The CT difference be-tween cortical phase and plain scan and excretory phase and parenchymal phase of AMLmf was significantly higher than that of PRCC,and the CT difference between parenchymal phase and cortical phase was significantly lower than that of PRCC(P<0.05).CT difference between cortical phase and plain scan and CT value difference between parenchymal phase and cortical phase and CT value difference between excretory phase and parenchymal phase of AMLmf were significantly lower than those of CCRCC(P<0.05).There were significant differences between AMLmf and ChRCC when talking about CT value difference of plain CT and cortical phase(P<0.05).The maximum diameter of AMLmf was significantly lower than that of PRCC and ChRCC(P<0.05).There were statistically significant differences between AMLmf and the three types of renal carcinoma in cleavage sign(ALL P<0.05).There were statistically significant differences between AMLmf and CCRCC in the uniformity of enhancement and the presence of cystic changes(P<0.05),but there were no statistically significant differences.Conclusion The differ-ence of CT values and CT signs of dynamic enhanced CT are helpful to distinguish AMLmf from three common types of renal car-cinoma.