The value of spectral CT in the hyperacute phase in predicting the occurrence of malignant cerebral edema in patients with large hemispheric infarction
The value of spectral CT in the hyperacute phase in predicting the occurrence of malignant cerebral edema in patients with large hemispheric infarction
Objective To explore the value of quantitative spectral CT in predicting the occurrence of malignant brain edema in patients with hyperacute phase large hemispheric infarction.Methods Thirty-five patients with large hemispheric infarction in the hyperacute stage who underwent spectral CT examination in Weihai Central Hospital were selected as observation subjects.The endpoint of this study was the occurrence of malignant cerebral edema,according to which the patients were divided into a malignant and non-malignant group of cerebral edema.The rates of net water uptake(NWU),iodine concentrations variation rate(ΔIC),and effective atomic number variation rate(ΔZeff)were calculated for the ischemic regions of the brain in both groups of patients.Comparing the differences between groups for each quantitative parameter,parameters with statistically significant differences were included in multifactor logistic regression and logistic regression models were constructed.The predictive effi-cacy of each quantitative parameter and regression model was assessed using subject operating characteristic(ROC)curves.Results The differences between NWU,ΔIC and ΔZeff groups were statistically significant(P<0.05),and all of them were positively correlated with malignant cerebral edema,and ΔIC was an independent predictor of the occurrence of malignant cere-bral edema.The area under the curve(AUC)of the regression model established by NWU,ΔIC and ΔZeff was 0.889,with a specificity of 88.24%.Conclusion The regression model established by the spectral CT quantitative parameters ΔIC and ΔZeff and the conventional CT quantitative parameter NWU has high accuracy in the prediction of malignant brain edema.
关键词
大面积脑梗死/体层摄影术,X线计算机/光谱成像/恶性脑水肿
Key words
Large hemispheric infarction/Tomography,X-ray computed/Spectral imaging/Malignant brain edema
维普
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