儿童颞骨横纹肌肉瘤的CT和MRI表现
CT and MRI findings of temporal bone rhabdomyosarcoma in children
邱健 1李晓燕 1丁宇 1姚利华 1秦永源 1黄炳乐 1曾凡勇 1李文华2
作者信息
- 1. 上海健康医学院附属崇明医院医学影像科 上海 202150
- 2. 上海健康医学院附属崇明医院医学影像科 上海 202150;上海交通大学医学院附属新华医院放射科 上海 200092
- 折叠
摘要
目的 探讨颞骨横纹肌肉瘤(RMS)的CT、MRI表现特征.方法 选取经手术病理证实的 7 例RMS的CT和MRI资料,对其起源部位、大小、边界、形态、信号特点、表观弥散系数(ADC)值和强化特征及免疫组织化学和Ki67 表达程度特征进行回顾性分析.结果 7 例患者中,起源于颞骨岩尖 3 例,岩骨体 2 例,中耳乳突区 2 例.肿瘤大小为 1.9 cm×2.1 cm×2.9 cm~8.1 cm×4.7 cm×3.9 cm,均呈不规则、边界清楚肿块,T1WI低信号、T2WI高信号,增强后呈均匀性强化 5 例、非均匀性强化 2 例,肿瘤ADC值范围为(0.89~1.04)×10-3 mm2/s,平均(0.92±0.07)×10-3mm2/s.肿瘤Ki67 表达程度范围为 50%~80%.结论 颞骨横纹肌肉瘤MRI表现为颞骨的溶骨性、边界清楚的软组织肿块,T1WI低信号、T2WI高信号,增强后呈明显强化,肿瘤细胞Ki67 均呈高表达为其典型特征.
Abstract
Objective To investigate CT and MRI imaging features of rhabdomyosarcomas(RMS)of the temporal bone.Methods CT,MR and immunohistochemical(IHC)data of 7 patients with RMS confirmed by surgical pathology were col-lected.The tumor location,size,boundary,shape,signal characteristics,apparent diffusion coefficient(ADC)value,enhance-ment characteristics and IHCindicators and Ki67 expression were retrospectively analyzed.Results Of those 7 patients,3 cases originated from petrous apex of temporal bone,2 cases from petrous body,and 2 cases from mastoid region of middle ear.The tumor size ranged from 1.9 cm×2.1 cm×2.9 cm-8.1 cm×4.7 cm×3.9 cm,with well-defined and irregular margins,low signal on T1WI,high signal on T2WI and homogeneous enhancement in 5 cases and heterogeneous enhancement in 2 cases.The ADC value of tumor ranged from 0.89 to 1.04(mean 0.92±0.07)×10-3mm2/s.Ki67 proliferative index was high in all tumors ranging from 50%to 80%.Conclusion RMS of temporal bone is osteolytic soft tissue mass,with clear margins,hypointensity on T1WI and hyperintensity on T2WIand DW imaging with strikingly enhancement and Ki67 highly expression.
关键词
颞骨/横纹肌肉瘤/体层摄影术,X线计算机/磁共振成像/儿童Key words
Temporal bone/Rhabdomyosarcoma/Tomography,X-ray computed/Magnetic resonance imaging/Children引用本文复制引用
出版年
2024