儿童颅脑Ⅰ型神经纤维瘤病的MRI应用价值
The value of MRI in children with craniocerebral neurofibromatosis type Ⅰ
程广 1覃文华 1卢林民 1马玉琴 1黄露1
作者信息
- 1. 广西柳州市妇幼保健院放射科 广西 柳州 545001
- 折叠
摘要
目的 探讨儿童颅脑Ⅰ型神经纤维瘤病(NF)的MRI应用价值.方法 选取 16 例确诊为Ⅰ型神经纤维瘤病(NF-Ⅰ型)的儿童头颅MRI影像资料进行回顾性分析.结果 1)MRI表现:发病部位包括基底节区 9 例,丘脑 8 例,海马6 例,小脑 11 例,脑干 8 例,眼眶/额叶 4 例;病变形态:类圆形 9 例,结节状 6 例,条状 5 例,点状 6 例,不规则状 4 例;MRI信号:T1WI呈低信号 6 例、等信号 10 例,T2WI高/稍高信号 16 例,FLAIR高/稍高信号 14 例,DWI等信号 16 例;MRS:Cho峰增高 2 例;NAA峰降低 2 例;2)合并症:蝶骨异常 2 例,眼球突出 2 例,脊柱侧弯 4 例,肺气囊 1 例.结论 儿童颅脑NF-I型的发病部位多为基底节区、丘脑、小脑及脑干,类圆形多见,T1WI呈等低信号,T2WI及FLAIR呈高/稍高信号,确诊需MRI与临床表现相结合.
Abstract
Objective To investigate the value of MRI in children with craniocerebral neurofibromatosis type Ⅰ.Methods The MRI images of 16 children with neurofibromatosis type Ⅰ were retrospectively analyzed.Results MRI findings were as fol-lows:9 cases were located in the basal ganglia,8 cases in thalamus,6 cases in hippocampus,11 cases in cerebellum,8 cases in brain stem,and 4 cases in orbital/frontal lobe.Pathological morphology were as follows:9 cases were quasi circular,6 cases were nodular,5 cases were strip shape,6 cases were punctate,and 4 cases were irregular.MRI showed that 6 cases had low sig-nal and 10 cases had equal signal on T1WI,16 cases had high/slightly high signal intensity on T2WI,14 cases had FLAIR high/slightly high signal,and 16 cases had DWI and other signals.MRS showed that Cho peak increased in 2 cases,NAA peak de-creased in 2 cases.As for complications,abnormal sphenoid bone was found in 2 cases,exophthalmos in 2 cases,scoliosis in 4 cases,and pulmonary air sac in 1 case.Conclusion The onset sites of type Ⅰ neurofibromatosis in children's brain are mostly basal ganglia,thalamus,cerebellum and brain stem.Quasi circular morphology is more common.Equal low signal on T1WI,high/slightly high signal on T2WI and FLAIR,and MRI should be combined with clinical manifestations for diagnosis.
关键词
儿童/颅脑/神经纤维瘤病/磁共振成像Key words
Children/Brain/Neurofibromatosis/Magnetic resonance imaging引用本文复制引用
出版年
2024
NETL
NSTL
万方数据