磁共振IVIM序列与单侧大脑中动脉闭塞所致急性大面积脑梗死的临床预后相关性分析
Correlation between magnetic resonance IVIM sequence and clinical prognosis of acute large area cerebral infarction caused by unilateral middle cerebral artery occlusion
辛奕 1薛明琛 1张亚运 1周胜利 2周芯羽3
作者信息
- 1. 南京医科大学康达学院附属连云港市第一人民医院影像科 江苏 连云港 222000
- 2. 江苏省连云港市灌南县第一人民医院影像科 江苏连云港 222006
- 3. 南京医科大学康达学院附属连云港市第一人民医院神经内科 江苏 连云港 222000
- 折叠
摘要
目的 探讨磁共振体素内不相干运动(IVIM)序列与单侧大脑中动脉(MCA)闭塞所致急性大面积脑梗死(ACI)临床预后的相关性.方法 选取我院 80 例单侧MCA闭塞所致大面积ACI患者的临床资料,均接受IVIM检查,所有患者出院后 90 天进行随访管理,通过mRS评分进行预后评估,比较不同预后患者IVIM检查参数(ADC值、f值、D值、D*值),分析IVIM检查参数(ADC值、f值、D值、D*值)与ACI预后的关联性.结果 两组性别、年龄、发病至MRI检查用时、吸烟情况、饮酒情况、高血脂、糖尿病、房颤、高血压情况差异无统计学意义(P>0.05),预后不良组入院时NIHSS分值高于预后良好组,差异有统计学意义(P<0.05).不同预后患者D*值间差异无统计学意义(P>0.05),预后不良患者ADC值、f值、D值低于预后良好患者,差异有统计学意义(P<0.05).经Pearson检验证实,D*值与ACI预后无显著相关性(P>0.05),ADC值、f值、D值与ACI预后存在显著正相关关系(P<0.05).结论 磁共振IVIM序列相关检查参数与单侧MCA闭塞所致ACI具有密切关联性,可通过IVIM检查对患者预后情况进行诊断评估,从而指导临床开展后续干预.
Abstract
Objective To investigate the correlation between magnetic resonance voxel incoherent motion(IVIM)sequences and the clinical prognosis of acute large area cerebral infarction(ACI)caused by unilateral middle cerebral artery(MCA)occlu-sion.Methods A retrospective selection was conducted on the clinical data of 80 patients with unilateral MCA occlusion caus-ing extensive ACI in our hospital.All patients underwent IVIM examination and were followed up for 90 days after discharge.Prognostic evaluation was conducted using mRS score.The IVIM examination parameters(ADC value,f value,D value,D *value)of patients with different prognosis were compared,and the correlation between IVIM examination parameters(ADC value,f value,D value,D * value)and ACI prognosis was analyzed.Results There was no significant difference between the two groups in terms of gender,age,time from onset to MRI examination,smoking,alcohol consumption,hyperlipidemia,diabe-tes,atrial fibrillation,and hypertension(P>0.05).The NIHSS score at admission in the poor prognosis group was higher than that in the good prognosis group(P<0.05).There was no significant difference in D * values among patients with different progno-sis(P>0.05),while the ADC values,f values,and D values of patients with poor prognosis were lower than those of patients with good prognosis(P<0.05).According to Pearson's test,there was no significant correlation between D * value and ACI prog-nosis(P>0.05),while,ADC value,f value,and D value were significantly positively correlated with ACI prognosis(P<0.05).Conclusion There is a close correlation between the parameters related to magnetic resonance IVIM sequence and ACI caused by unilateral MCA occlusion.IVIM examination can be used to diagnose and evaluate the prognosis of patients,thus guiding clinical follow-up interventions.
关键词
磁共振成像/磁共振体素内不相干运动序列/单侧大脑中动脉闭塞/急性大面积脑梗死Key words
Magnetic resonance imaging/Magnetic resonance voxel incoherent motion sequence/Unilateral occlusion of the middle cerebral artery/Acute massive cerebral infarction引用本文复制引用
基金项目
江苏省连云港市卫生科技项目(ZD202202)
南京医科大学康达学院科研发展基金重点项目(KD2023KYJJ033)
出版年
2024
NETL
NSTL
万方数据