摘要
目的 探讨儿童单核细胞李斯特菌脑膜炎MRI表现.方法 选取我院住院的18例单核细胞李斯特菌脑膜炎患儿病历资料和MRI资料进行临床及影像学分析.结果 18例患儿中12例有脑膜、室管膜、脉络丛或颅神经强化.其他征象包括硬膜下积液、脑积水、脑室系统增宽、脑外间隙增宽、脑沟增宽加深.13例经磁共振血管成像(MRA)和磁共振静脉造影(MRV)扫描的单核细胞李斯特菌脑膜炎患儿中,MRA未发现阳性征象,3例MRV有阳性征象(静脉窦细、额部上矢状窦信号增高).结论 单核细胞李斯特菌脑膜炎多发生于幼儿,MRI表现脑膜强化合并颅神经强化具有特异性,可以为临床早期诊断提供参考.
Abstract
Objective To analyze the MRI manifestations of children with Listeria monocytogenes meningitis.Methods We selected medical records and head MRI data of children with Listeria monocytogenes meningitis admitted to the Department of Infectious Diseases in our hospital for clinical and imaging analysis.Results Among 18 children with Listeria monocyto-genes meningitis,12 cases had enhancement of the meninges,ependyma,choroid plexus,or cranial nerves.Other signs in-cluded subdural effusion,hydrocephalus,widening of the ventricular system,widening of the extracerebral space,and widening and deepening of the cerebral sulcus.Among 13 children with monocytic Listeria meningitis who underwent MRA and MRV scans,no positive signs were found on MRA,while,3 cases had positive signs on MRV(thin venous sinus and increased signal in the frontal sagittal sinus).Conclusion Listeria monocytogenes meningitis is more common in young children,and the MRI findings of the meningeal enhancement combined with cranial nerve enhancement have specificity,which can provide reference for early clinical diagnosis.
基金项目
国家自然科学基金资助项目(12171330)
科技创新2030-"脑科学与类脑研究"重大项目(2021ZD0200508)
北京市医院管理中心"登峰"人才培养计划项目(DFL20221002)