超声造影与增强CT在肝癌诊断和微波消融疗效评估中的应用分析
Application of contrast-enhanced ultrasound and enhanced CT in diagnosis of liver cancer and evaluation of microwave ablation
孔生 1韩雯雯 2孔淑红 2任玉洁 2岳学旺2
作者信息
- 1. 山东颐养健康集团莱芜中心医院超声科 山东 济南 271103
- 2. 山东省东营市人民医院医学影像科 山东 东营 257091
- 折叠
摘要
目的 探讨超声造影(contrast-enhanced ultrasound,CEUS)和增强CT在肝癌诊断和微波消融(MWA)疗效评估中的应用.方法 选取 79 例肝癌患者,所有患者均接受CEUS和增强CT检查.以病理检查为金标准,比较两种方法诊断的一致性.MWA治疗后对患者进行CEUS和增强CT疗效评估,并比较两种诊疗方法的一致性.结果 CEUS与增强CT的诊断准确率差异无统计学意义(P>0.05).CEUS和增强CT显示,病变的最大横截面积差异无统计学意义(P>0.05),而且在治疗前、治疗 1 个月和 3 个月后的疗效评估,两种方法之间差异无统计学意义(P>0.05).Bland-Altman检验结果显示,在治疗 1 个月和 3 个月后测量的病变最大横截面积中,CEUS与增强CT之间具有高度的一致性.线性回归分析显示,CEUS测量的最大截面积与增强CT检测的最大截面积呈显著相关性.结论 CEUS的诊断效率与增强CT的诊断效率相同,两者均表现出相当高的灵敏度和特异度.两种方法评估MWA疗效呈高度一致性.CEUS可以实现局部血流灌注的实时观察,更经济实惠且方便.
Abstract
Objective This study investigated the application effect of contrast-enhanced ultrasound(CEUS)and enhanced CT in diagnosis of liver cancer and response evaluation of microwave ablation.Methods A total of 79 patients with liver cancer were all subjected to CEUS and enhanced CT.With pathological examination as the gold standard,diagnostic consistency of the two methods was compared.After microwave ablation,patients were subjected to CEUS and enhanced CT to assess the efficacy,and the consistency was compared.Results There was no significant difference in diagnostic accuracy between CEUS and CT(P>0.05).No significant difference in the maximal cross-sectional area of lesions was found between CEUS and enhanced CT,and there was no significant difference in evaluation of therapeutic efficiency between the two methods(P>0.05)before and 1 and 3 months after treatment.Bland-Altman test showed that there was a strong consistency between CEUS and enhanced CT in the measured maximum cross-sectional area of lesions at 1 and 3 months after treatment.Linear regression analysis showed that maximum section cross-sectional area measured by CEUS was significantly correlated with that detected by enhanced CT.Con-clusion The results suggest that diagnostic efficiency of CEUS is similar to that of enhanced CT,and both show high sensitivity and specificity.Two methods show high consistency in evaluating the curative effect of MVA.CEUS can achieve real-time obser-vation of focal blood flow perfusion,which is more economically affordable and convenient.
关键词
超声造影/体层摄影术,X线计算机/肝癌Key words
Contrast-enhanced ultrasound/Tomography,X-ray computed/Liver cancer引用本文复制引用
基金项目
山东省医药卫生科技发展计划项目(202103010741)
出版年
2024
NETL
NSTL
万方数据