原发性及转移性腺泡状软组织肉瘤临床及影像学特点
Clinical and imaging characteristics of primary and metastatic alveolar soft part sarcoma
许还予 1潘志立 1夏睿2
作者信息
- 1. 中国科学技术大学附属第一医院 放射科 安徽 合肥 230001
- 2. 中国科学技术大学附属第一医院 创伤骨科 安徽 合肥 230001
- 折叠
摘要
目的 探讨腺泡状软组织肉瘤(ASPS)及其转移灶的临床特征及影像学表现.方法 选取经病理证实的 15例ASPS患者资料,分析病灶部位、大小、形态、密度、信号、强化、毗邻关系、转移特征及随访情况.结果 15 例患者中原发性 6 例,继发性 9 例,发病中位年龄 25 岁;原发肿瘤部位:下肢 10 例,上肢 2 例,髂窝 1 例,腹壁 1 例,颈部 1 例.肿瘤体积较大,CT和 MRI平扫呈不均匀密度信号,增强均呈显著不均匀强化,肿瘤内部及周围见多发迂曲增粗血管影.患者中 12 例肺转移,5 例骨转移,4 例淋巴结转移,2 例肝转移,2 例脑转移,增强部分病灶明显强化.结论 ASPS发病年龄较小,生长缓慢,多好发于下肢,增强后瘤周及瘤内明显增粗增多的血管影为其影像学特征,易转移,肺转移最常见.
Abstract
Objective To investigate the clinical characteristics and imaging manifestations of alveolar soft part sarcoma(ASPS)and its metastatic lesions.Method A retrospective analysis was conducted on a total of 15 patients with ASPS con-firmed by pathology.The lesion location,size,morphology,density,signal,enhancement,adjacent relationship,metastasis,and follow-up were recorded,and the characteristics were su mmarized summarized.Results Among the 15 patients,6 were primary and 9 were secondary,with a median age of 25 years.Primary tumor location was as follows:10 tumors were located in the lower limbs,2 in the upper limbs,1 in the iliac fossa,1 in the abdominal wall,and 1 in the neck.The tumor had a large vol-ume,and CT and MR plain scans showed uneven density/signal,with significant uneven enhancement.Multiple tortuous and thickened vascular shadows were seen inside and around the tumor.Among the metastatic cases,there were 12 cases of lung me-tastasis,5 cases of bone metastasis,4 cases of lymph node metastasis,2 cases of liver metastasis,and 2 cases of brain metasta-sis,some of which were significantly strengthened.Conclusion ASPS has a younger onset age,slower growth,and is more likely to occur in the lower limbs.The imaging features of ASPS include significantly thickened and increased vascular shadows around and within the tumor after enhancement,which are prone to metastasis,with lung metastasis being the most co mmon.
关键词
腺泡状软组织肉瘤/体层摄影术,X线计算机/磁共振成像Key words
Alveolar soft part sarcoma/Tomography,X-ray computed/Magnetic resonance imaging引用本文复制引用
基金项目
安徽省社会科学创新发展研究课题(2021CX121)
安徽省重点研究与开发计划项目(2022i01020017)
安徽省教育厅高等学校省级质量工程项目(2022jyxm1840)
中国科学技术大学校级质量工程项目(2022xjyxm069)
出版年
2024
NETL
NSTL
万方数据