摘要
探讨肿瘤患者参加药物临床试验的动机以及影响因素.采用描述性质性研究方法,对 16 名参加药物临床试验的肿瘤患者进行深入访谈,运用内容分析法对访谈资料进行整理分析.共归纳出 2 个主题:参与动机(包括对新药治疗的希望、医生建议参与药物临床试验、减轻经济负担、为社会作贡献)、影响因素(包括家人及亲朋好友的反对、对治疗效果的担忧、对药物不良反应的恐惧、药物临床试验相关知识缺乏、时间及交通不便).因此,研究人员应从患者的角度出发,加强沟通交流,避免治疗性误解,帮助患者理性参与决策,减少患者的参与阻碍因素,以促进受试者招募.
Abstract
This study explored the motivation and influencing factors of oncology patients to participate in drug clinical trials.A descriptive qualitative research method was used to conduct in-depth interviews with 16 oncology patients who participated in drug clinical trials,and the interview data were collated and analyzed using content analysis.Two main themes were identified:motivation for participation(including hope for new drug treatment,doctor's suggestion to participate in drug clinical trials,reducing financial burden,and contributing to society),and influencing factors(including opposition from family and close friends,concern about treatment effects,fear of adverse drug reactions,lack of knowledge related to drug clinical trials,and inconvenience of time and transportation).Therefore,researchers should take the patient's perspective,enhance communication,avoid therapeutic misunderstandings,help patients make rational decisions about participation,and reduce the obstacles to patient participation in order to facilitate subject recruitment.
基金项目
西南医科大学校级科研项目(2021)(2021ZKQN065)
四川省科技厅科技创新基地(平台)项目(2019)()
人才计划(2019JDKP0014)
NETL
NSTL
万方数据