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异种器官移植试验性治疗的伦理研究

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在对基因编辑猪器官移植试验性治疗伦理评估基础上,提出建构试验性治疗的伦理规范能保障患者利益、避免医患冲突、减少器官捐献的伦理问题和有利于医学科学知识的进步.但是,临床研究和临床治疗区分方式导致试验性治疗伦理规范的缺失,通过"同情使用"的简单条件规范并不能指导异种器官移植试验性治疗.因此,从临床研究和临床治疗整合基础上提出异种器官移植试验性治疗的伦理框架,希望为以后异种器官移植试验性治疗伦理规范的完善提供基础.
Ethical Research on Experimental Treatment of Xenotransplantation
Based on the ethical evaluation of experimental treatment of gene-edited pig organ transplantation,this paper proposes that the construction of ethical norms for experimental treatment can protect the interests of patients,avoid doctor-patient conflicts,reduce the ethical issues of organ donation,and is conducive to the advancement of medical scientific knowledge.However,the distinction between clinical research and clinical treatment has led to the lack of ethical norms for experimental treatment.Simple conditional norms of"compassionate use"cannot guide experimental treatment for xenotransplantation.Therefore,this paper proposes an ethical framework for experimental treatment of xenotransplantation based on the integration of clinical research and clinical treatment,hoping to provide a basis for the improvement of ethical norms for experimental treatment of xenotransplantation in the future.

xenotransplantationexperimental treatmentclinical researchethical framework

马晶

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南京中医药大学医学人文学院 江苏南京 210023

异种器官移植 试验性治疗 临床研究 伦理框架

江苏省高等学校哲学社会科学研究一般项目(2023)高水平大学建设项目开放课题(2022)

2023SJYB03322022ZYWH017

2024

医学与哲学
中国自然辩证法研究会

医学与哲学

CSTPCDCHSSCD北大核心
影响因子:1.314
ISSN:1002-0772
年,卷(期):2024.45(9)
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