Malaria has long plagued the border areas of Yunnan inhabited by ethnic minorities,within a complex multicultural backdrop.Ethnic cultural factors significantly hinder the prevention and treatment of malaria in Yunnan.Widespread beliefs in spirits and shamanic ritual therapies are particularly detrimental,leading to misconceptions among ethnic minorities regarding the causes,treatment,prevention,choice of medical practitioners,and social responses to malaria.These cultural factors contribute to making malaria control in Yunnan"extremely challenging".Behind this phenomenon are factors such as human interests,power dynamics,and cultural characteristics,all influencing the situation.Therefore,in addition to providing conventional medical care and effective drugs,malaria control in Yunnan also requires a focus on cultural adaptation in healthcare practices and involves a process of demystifying the disease.