摘要
潜伏性结核感染有发展为活动性结核病可能,长周期的预防性抗结核治疗存在诊疗方案不统一、医疗费用高、各种不同程度的药物不良反应等问题.以西安市某结核病专科医院2021-2023年潜伏性结核感染门诊患者为研究对象,分析讨论潜伏性结核感染在预防性治疗中面临的医学困境.针对目前潜伏性结核感染患者人次逐年成倍增加、患病人群年轻化、以女性为主、≥90%患者为自费支付这些现状,需制定潜伏性结核感染诊疗标准、减少不良反应发生;保证患者对长周期规范性治疗的充分知情;完善医保支付范畴,减少个人经济负担,尤其对育龄期妇女进行专项资助等,为潜伏性结核感染的临床诊疗和有效防控提供实践参考.
Abstract
Latent tuberculosis infection(LTBI)carries the risk of progressing to active tuberculosis,and its long-term prophylactic treatment is fraught with challenges,such as inconsistent treatment protocols,high medical costs,and varying degrees of adverse drug reactions.This study focuses on the patients of a tuberculosis specialty hospital in Xi'an from 2021-2023,analyzing the medical dilemmas faced by LTBI in prophylactic treatment.The current situation is that the number of LTBI patients is increasing exponentially year by year,the younger demographic,predominance of female patients,and over 90% of the patients are self-paying.It is necessary to establish standardized diagnostic and treatment protocols for LTBI,minimize adverse reactions,ensure that patients are fully informed of the long-term standardized treatment,expand insurance coverage to reduce individual financial burdens,and provide special financial support for women of childbearing age.These strategies aim to provide practical references for clinical diagnosis and treatment,as well as for the effective prevention and control of LTBI.
基金项目
2023年陕西省一般项目社会发展领域基金项目(2023-YBSF-336)
2024年陕西省一般项目社会发展领域基金项目(2024SF-YBXM-693)