3.0TMR动态增强成像在前列腺癌诊断中的应用研究
3 T dynamic contrast-enhanced MRI diagnosis of prostate cancer
章绪辉 1全显跃 1路世龙 1黄凡衡1
作者信息
- 1. 510280广东广州，南方医科大学珠江医院放射科
- 折叠
摘要
目的探讨3.0 T MR动态增强成像（DCE-MRI）在前列腺癌诊断中的应用价值。方法收集疑诊前列腺癌者75例，所有患者均行T2 WI和DCE-MRI检查。分析比较T2 WI和DCE-MRI对前列腺癌诊断敏感性、特异性和准确性的差异，并分析DCE-MRI对前列腺癌的检出率和Gleason评分的相关性。结果前列腺癌患者44例，T2 WI和DCE-MRI对前列腺癌诊断的敏感性、特异性和准确性分别为64%和91%、58%和77%、61%和85%。DCE-MRI诊断敏感性和准确性明显高于T2 WI（P＜0.01），而特异性未见明显高于T2 WI（P＞0.05）。DCE-MRI对高分化组Gleason评分＜7分的前列腺癌检出率明显低于对中低分化组Gleason评分≥7分的前列腺癌（P＜0.05）。结论和T2 WI相比，3.0 T DCE-MRI能明显提高对前列腺癌的诊断敏感性和准确性。而且，DCE-MRI更容易检出中低分化的前列腺癌。
Abstract
Objective To evaluate the diagnostic accuracy of 3 T dynamic contrast-enhanced MRI(DCE-MRI)for prostate cancer.Methods 75 patients with clinical suspicion of prostate cancer underwent T2-weighted MR imaging(T2WI)and DCE-MRI.The sensitivity,specificity and accuracy of T2WI and DCE-MRI for diagnosing prostate cancer were determined.The relationship between Gleason score and prostate cancer detection on DCE-MRI was also evaluated.Results Of 75 patients,prostate adenocarcinoma was confirmed histopathologically in 44.The sensitivity and accuracy of DCE-MRI(91%,85%)were significantly (P<0.01)higher than those of T2WI(64%,61%).The specificity of DCE-MRI(77%)was not significantly(P>0.05)higher than that of T2WI(58%).The detection rate for Gleason 4-6 cancers was significantly lower than that for Gleason 7-9 cancers(P<0.05). Conclusion 3 T DCE-MRI is superior to T2WI in prostate cancer detection and can detect more aggressive tumors.
关键词
前列腺癌/T2加权成像/磁共振成像/动态增强/Gleason评分Key words
Prostate cancer/T2 Weight imaging/Magnetic resonance imaging/Dynamic enhancement/Gleason scale引用本文复制引用
出版年
2014
NETL
NSTL
万方数据