巴马香猪原位肾脏移植模型的建立及手术方式效果对比
Establishment of orthotopic kidney transplantation model and comparison of different vascular anastomosis methods in Bama Xiang pigs
韩士超 1马帅军 1戚若晨 1王国辉 1张小燕 1刘克普 1范效铮 1魏迪 1杨晓剑 1秦卫军1
作者信息
- 1. 空军军医大学西京医院泌尿外科,陕西西安 710032
- 折叠
摘要
目的 构建猪-猪原位肾脏移植模型并探讨不同血管吻合方式的效果以及并发症发生率.方法 采用整块供肾切取术获取肾脏,移植肾修整后,行移植肾动静脉与受体猪动静脉端端吻合的原位肾移植.根据血管吻合方式不同,分为传统吻合组(n=12)和显微吻合组(n=12),比较两组动脉吻合时间、静脉吻合时间、总体手术时间、肾脏冷缺血时间、肾脏热缺血时间以及血管相关并发症发生率.结果 传统吻合组动脉吻合时间、静脉吻合时间、总体手术时间、肾脏冷缺血时间均低于显微吻合组,传统吻合组血管并发症发生率高于显微吻合组.结论 猪-猪原位肾脏移植模型具有较强的可操作性且供受者间肾动静脉显微吻合有助于减少移植肾血管并发症.
Abstract
Objective To establish porcine orthotopic kidney transplantation model and investigate the effect and complication rate of different vascular anastomosis methods.Methods The kidney was obtained by whole donor nephrectomy.After kidney repairment of the transplanted kidney,orthotopic kidney transplantation was performed with end-to-end anastomosis between the arteries/veins of the transplanted kidney and the arteries/veins of the recipient pigs.According to different vascular anastomosis methods,the recipient pigs were divided into traditional anastomosis group(n=12)and micro-anastomosis group(n=12).Arterial anastomosis time,venous anastomosis time,total operation time,renal warm ischemia time,renal cold ischemia time and incidence of vascular complications were compared between the two groups.Results Arterial anastomosis time,venous anastomosis time,total operation time and renal cold ischemia time in the traditional anastomosis group were lower than those in the micro-anastomosis group,and the incidence of vascular complications in the traditional anastomosis group was higher than that in the micro-anastomosis group.Conclusion Porcine orthotopic kidney transplantation model has strong operability and renal arteriovenous micro-anastomosis can reduce vascular complications of transplanted kidney.
关键词
原位肾移植/血管吻合/移植效果/模型建立Key words
orthotopic kidney transplantation/vascular anastomosis/transplantation effect/model establishment引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
维普
万方数据