空军军医大学学报2024,Vol.45Issue(2) :193-197.DOI:10.13276/j.issn.2097-1656.2024.02.013

经皮耳迷走神经刺激对恐惧情绪的实时干预效果研究

Study on real-time intervention effect of transcutaneous auricular vagus nerve stimulation on fear

黄美清 丛林 宋春杨 程珊 熊凯文 马进 胡文东
空军军医大学学报2024,Vol.45Issue(2) :193-197.DOI:10.13276/j.issn.2097-1656.2024.02.013

经皮耳迷走神经刺激对恐惧情绪的实时干预效果研究

Study on real-time intervention effect of transcutaneous auricular vagus nerve stimulation on fear

黄美清 1丛林 1宋春杨 2程珊 1熊凯文 1马进 1胡文东1
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作者信息

  • 1. 空军军医大学航空航天医学系航空航天医学装备教研室,陕西西安 710032
  • 2. 解放军第95926部队卫生队,吉林长春 130103
  • 折叠

摘要

目的 探索经皮耳迷走神经刺激(taVNS)不同刺激强度对恐惧情绪的实时干预效果.方法 本研究筛选80名被试,随机分为4组,每组20名,分别接受不同强度的taVNS.采用基于VR的恐惧诱发平台诱发恐惧情绪,通过绩效评估、生理变化和主观量表评分考察实时干预效果.结果 绩效评估方面,30%刺激组的行走距离显著高于10%刺激组(P<0.01),10%刺激组和30%刺激组的九灯任务正确率显著高于伪刺激组(P<0.05),30%刺激组的平均按键反应时显著低于伪刺激组平均按键反应时(P<0.05);生理变化方面,30%刺激组的呼吸率显著高于10%刺激组的呼吸率(P<0.01);主观量表评分方面,伪刺激组的后测分数显著高于30%刺激组的后测分数(P<0.05).结论 taVNS可能会降低恐惧情绪的强度,在本研究taVNS的不同刺激强度中,30%刺激强度为恐惧情绪实时干预的最优参数.

Abstract

Objective To investigate the real-time intervention effect of transcutaneous auricular vagus nerve stimulation(taVNS)with different stimulation intensities on fear.Methods In this study,80 subjects were selected and randomly divided into 4 groups(20 subjects in each group)to receive different intensities of taVNS.A VR-based fear induction platform was used to induce fear,and the real-time intervention effect was investigated through performance evaluation,physiological changes and subjective scale scores.Results In terms of performance evaluation,the walking distance of 30%stimulation group was significantly higher than that of 10%stimulation group(P<0.01),the accuracy rate of the nine-light task of 10%stimulation group and 30%stimulation group was significantly higher than that of pseudo-stimulation group(P<0.05),and the average key reaction time of 30%stimulation group was significantly lower than that of pseudo-stimulation group(P<0.05).In terms of physiological changes,the respiratory rate of 30%stimulation group was significantly higher than that of 10%stimulation group(P<0.01).As for subjective scale scores,the posttest score of pseudo-stimulation group was significantly higher than that of 30%stimulation group(P<0.05).Conclusion taVNS may reduce the intensity of fear.Among the different stimulation intensities of taVNS in this study,30%stimulation intensity is the optimal parameter for real-time intervention of fear.

关键词

经皮耳迷走神经刺激/恐惧情绪/实时干预/心率

Key words

transcutaneous auricular vagus nerve stimulation/fear/real-time intervention/heart rate

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基金项目

国家自然科学基金(U1933201)

国家自然科学基金(72101262)

陕西省重点研发计划项目(2022SF-052)

出版年

2024
空军军医大学学报
第四军医大学

空军军医大学学报

CHSSCD
影响因子:0.372
ISSN:2097-1656
参考文献量20
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