空军军医大学学报2024,Issue(3) :292-297.DOI:10.13276/j.issn.2097-1656.2024.03.009

内镜下纵行切开联合曲安奈德注射治疗化学烧伤性食管狭窄的特征分析及效果评价

Characteristic analysis and effect evaluation of endoscopic longitudinal incision combined with triamcinolone injection in the treatment of caustic esophageal stenosis

陈虹羽 徐梦楠 张静 郭瑞 陈晓 李曼华 张小朋 银新 李白容 孙涛 范崇熙 宁守斌
空军军医大学学报2024,Issue(3) :292-297.DOI:10.13276/j.issn.2097-1656.2024.03.009

内镜下纵行切开联合曲安奈德注射治疗化学烧伤性食管狭窄的特征分析及效果评价

Characteristic analysis and effect evaluation of endoscopic longitudinal incision combined with triamcinolone injection in the treatment of caustic esophageal stenosis

陈虹羽 1徐梦楠 2张静 2郭瑞 2陈晓 2李曼华 2张小朋 2银新 2李白容 2孙涛 2范崇熙 2宁守斌1
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作者信息

  • 1. 安徽医科大学空军临床学院消化内科, 北京 100142;空军特色医学中心消化内科, 北京 100142
  • 2. 空军特色医学中心消化内科, 北京 100142
  • 折叠

摘要

目的 探讨内镜下纵行切开联合曲安奈德注射治疗化学烧伤性食管狭窄的疗效及可行性.方法 选取2019 年 2 月至 2023 年 2 月在空军特色医学中心接受内镜下纵行切开联合曲安奈德注射治疗的 15 例化学烧伤性食管狭窄患者的临床资料进行回顾性观察.结果 15 例患者共接受内镜治疗 59 次,平均手术用时(31.73±11.36)min,切开狭窄长度(7.53±4.88)cm,治疗过程中有6 例合并支架置入,末次治疗结束 8 周后吞咽困难情况及BMI明显改善,总有效率 80%,且末次治疗后 6 个月 60%(9/15)患者Stooler分级为 0~1 级.59 次治疗过程中有 3 次出现肌层损伤或微小穿孔,均给予术中钛夹封闭,无其他内镜治疗相关严重并发症.结论 内镜下纵行切开联合曲安奈德注射治疗化学烧伤性食管狭窄的短期内安全、有效,但其长期疗效仍有待随访观察.

Abstract

Objective To investigate the efficacy and feasibility of endoscopic longitudinal incision combined with triamcinolone injection in the treatment of caustic esophageal stenosis.Methods The clinical data of 15 patients with caustic esophageal stenosis who received endoscopic longitudinal incision combined with triamcinolone injection at Air Force Medical Center from February 2019 to February 2023 were retrospectively observed.Results The 15 patients received 59 times of endoscopic treatment,with an average operation time of(31.73±11.36)min and incision stenosis length of(7.53±4.88)cm.In the course of treatment,6 patients were combined with stent implantation.The dysphagia and BMI were significantly improved 8 weeks after the end of the last treatment,and the overall effective rate was 80%.Within 6 months after the last treatment,60%(9/15)of the patients had the Stooler score from 0 to 1.In the 59 treatments,muscle injury or minor perforation occurred in 3 times,all of which were closed with titanium clips,and there were no other serious complications related to endoscopic therapy.Conclusion Endoscopic longitudinal incision combined with triamcinolone injection is safe and effective in the short term for the treatment of caustic esophageal stenosis,but its long-term efficacy remains to be observed.

关键词

化学烧伤性食管狭窄/内镜下纵行切开/曲安奈德注射/Stooler分级/疗效评价

Key words

caustic esophageal stenosis/endoscopic longitudinal incision/triamcinolone injection/Stooler score/effect evaluation

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基金项目

北京市科技计划项目(Z221100007422061)

空军军医大学临床研究项目(2021LC2201)

出版年

2024
空军军医大学学报
第四军医大学

空军军医大学学报

CHSSCD
影响因子:0.372
ISSN:2097-1656
参考文献量27
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