Objective To explore the application effect of home-based exercise training under the guidance of WeChat in the treatment of temporomandibular joint disorders(TMD).Methods A total of 120 TMD patients admitted to Stomatological Hospital,Air Force Medical University from October 2020 to October 2021 were randomly divided into control group(n=60)and observation group(n=60).The control group was given routine guidance for home-based exercise training,while the observation group was given comprehensive guidance based on WeChat for home-based exercise training.Visual Analogue Scale(VAS),maximum mouth opening(MMO)and Mandibular Function Impairment Questionnaire(MFIQ)were evaluated before treatment,at the end of treatment and at 6 months after treatment in both groups,and compliance with home-based exercise training was investigated at the end of treatment.Results There was no significant difference in the scores of VAS,MMO and MFIQ between the two groups before treatment(P>0.05).VAS and MFIQ scores in observation group were lower than those in control group at the end of treatment and 6 months after treatment(P<0.05),while MMO values were higher than those in control group(P<0.05).The compliance score,confidence in completing the training and satisfaction degree of the training guidance method in observation group were better than those in control group(P<0.01).Conclusion Remote guidance by WeChat is helpful to maintain the continuity of rehabilitation treatment,and accelerate the improvement of symptoms,which can ensure the effect of home-based exercise training for TMD.