葛根素联合阿魏酸钠治疗急性脑梗死的疗效观察
Clinical Observation of Acute Cerebral Infarction Treated by Puerarin Combined with Sodium Ferulate
谢宁 1王静1
作者信息
- 1. 娄底市中心医院神经内科,湖南,娄底,417000
- 折叠
摘要
目的观察葛根素联合阿魏酸钠治疗脑梗死的临床疗效.方法选择发病72 h内的脑梗死患者68例,随机分成治疗组(34例)和对照组(34例).治疗组给予常规治疗加葛根素注射液和阿魏酸钠,每日1次,连用15 d.对照组仅用常规治疗和同剂量、同疗程的葛根素注射液,疗程结束后对所有患者进行神经功能缺损评分、生活能力状态评分、血液流变学等指标的变化情况.结果治疗后,治疗组与对照组比较,其神经功能缺损评分和生活能力状态评分有统计学意义(P<0.05);血液流变学明显改善(P<0.05).治疗组总有效率为97%,显效率为85.2%;对照组的总有效率为85.2%,显效率为64.7%.两组疗效比较有显著性差异(P<0.05).结论葛根素联合阿魏酸钠治疗脑梗死临床疗效较好,安全性高.
Abstract
Objective To evaluate the clinical observation of acute cerebral infarction treated by puerarin combined with sodium ferulate. Methods A total of 68 patients with acute cerebral infarction in 72 hours were included. The patients were randomly assigned to treatment group( 34 cases ) and control group( 34 cases ). In addition to the common treatment,each patient of the treatment group was treated with puerarin combined with sodium ferulate, whereas each patient of the control group was only treated with puerarin. 1 time per day, 15 days altogether. After the treatment, evaluation parameters was used by the neurological deficit scale scores, the activities of daily living, the hemorheology changes and so on. Results The efficacy of the treatment group was better than the control group. Differences of the neuroloical deficit scale scores, and activities of daily living were statistically significant( P ＜ 0.05 ); hemorheology performance was noticeably better( P ＜ 0.05 ). Total effective rate of the treatment group was 97％ , obviously effective rate was 85.2％; while the corresponding numbers of the control group were 85.2％ and 64.7％ respectively. Conclusion Puerarin combined with sodium ferulate as treatment for acute cerebral infarction is an more effective and safer method.
关键词
葛根素/阿魏酸钠/急性脑梗死/疗效Key words
Puerarin/Sodium ferulate/Acute cerebral infarction/Efficacy引用本文复制引用
出版年
2011
NETL
NSTL
维普
万方数据