摘要
目的 探析肺功能检测在肺结核治疗中的临床应用.方法 入选2012年7月至2014年7月石家庄市第五医院肺结核患者及慢性阻塞性肺疾病患者使用德国产耶格肺功能机进行肺功能检测,各项数据计算均由本机附带电子计算机自动进行.试验1:选取100例按性别分为两组:女性肺结核患者50例,男性肺结核患者50例,经过为期半年的治疗后,比较两组治疗前后肺功能检测结果.试验2:按不同病理类型选择160例分为4组,浸润性肺结核组(50例),慢性纤维空洞性肺结核组(50例),粟粒性肺结核组(30例)、支气管结核组(30例),经过为期半年的治疗后,比较4组治疗前后肺功能检测结果.试验3:按疾病选择130例分为3组:肺结核组(50例),慢性阻塞性肺疾病组(50例),肺结核合并慢性阻塞性肺疾病组(30例),经过为期半年的治疗后,对各组肺结核患者进行肺功能检查,比较各组治疗前后肺功能[第1秒用力呼气量(FEV1)、用力肺活量(FVC)、最大通气量(MVV)、FEV1占FVC百分率(FEV1/FVC)、残气量(RV)、肺总量(TLC)、残总比(RV/TLC)及一氧化碳弥散量(DLC)]情况.结果 试验1,男性治疗后FEV1、FVC、MW显著优于女性肺功能指标,差异有统计学意义(P＜0.05);试验2,浸润性肺结核治疗后FVC、MVV、FFV1/FVC显著优于其他病理类型肺功能指标,差异有统计学意义(P＜0.05);支气管结核型与慢性纤维空洞性肺结核治疗后的肺功能指标差异无统计学意义,粟粒性肺结核肺功能指标最差,差异有统计学意义(P＜0.05);试验3,肺结核组治疗后FVC、FFV1/FVC％显著优于慢性阻塞性肺疾病组、肺结核合并慢性阻塞性肺疾病组,差异有统计学意义(P＜0.05).结论 肺结核治疗中检测肺功能可评估病情严重程度及临床效果,是治疗转归的敏感指标.
Abstract
Objective To explore and analyze the clinical application of lung function testing in the treatment of tuberculosis(TB).Methods Selected from Jul.2012 to Jul.2014 in Shijiazhuang Fifth Hospital,TB patients was tested lung function by use of Germany Jaeger pulmonary function machine, the data was calculated bythe computer with the machine automatically.Trial 1 : 100 cases,including 50 female and 50 male,and lung function was compared after half a year's of treatment.Trial 2 : 160 cases of different pathological types were divided into four groups,infiltrative pulmonary TB group(50 cases), chronic pulmonary TB hollow fiber group(50 cases), miliary TB group(30 cases) ,bronchial TB group(30 cases), and lung function was corpared after half a year's of treatment.Trial 3130 cases of different disease were divided into 3 groups,TB group(50 cases), chronic obstructive pulmonary disease(COPD) group(50 cases), TB and COPD group(30 cases), the lung function before and after treatment [The first second forced expiratory volume (FEV1) ,forced vital capacity(FVC) ,maximal voluntary ventilation(MVV) ,the FEV1 accounted for FVC pe rcentage(FEV1/FVC), residual volume(RV) ,total lung capacity(TLC) RV/TLC, and diffusion capacityfor carbon monoxide(DLC)] of different groups were compared.Results Trial 1, male lung function indicators(FEV1 , FVC, MVV) was significantly better than women after treatment, the differences were statistically significant(P ＜0.05);Trial 2, the FVC, MVV, FFV1/FVC of invasive TB were significantly better than the other pathological type, the differences were statistically significant(P ＜0.05);bronchial TB patients and chronic pulmonary TB hollow fiber patients had no significant differences in the above indexes, miliary TB had worst indexes thedifferences were statistically significant(P ＜ 0.05);trial 3, FVC, FFV1/FVC of TB group was significantly better than COPD group, and TB and COPD group,the differences were statistically significant(P ＜ 0.05).Conclusion Lung function tests in TB treatment can assess the severity and clinical effect of the diseases,which is a sensitive indicator of the treatment outcome.
NETL
NSTL
维普
万方数据