Visual analysis of neuropilin-1 studies based on CiteSpace
Objective To analyze the current status,hotspots,and trends of neuropilin-1 research using CiteSpace.Methods The relevant literatures on NRP1 in CNKI,Wanfang Data,VIP and Web of Science core collection database were searched from the establishment of the database to September 2022,and keywords were visualized and analyzed by using CiteSpace.Results A total of 536 Chinese and 2444 English literatures were included,and the annual number of published documents showed a fluctuating upward trend.Yan Jianghua and Han Zhengxiang had published the most papers in Chinese literature,while Ruhrberg and Christiana had published the most papers in English.Xiamen University and Harvard University were the institutions with the largest number of Chinese and English literature publications respectively,gastric cancer,angiogenesis,and breast cancer were hot topics in Chinese,while expression,receptor,and endothelial growth factor were hot topics in English.Conclusion The research of NRP1 is still in the development stage,and the research hotspot and trend are mechanism and clinical research.Cooperation between teams should be strengthened to make research more systematic.