Exploration the prescription and medication rules of ancient Chinese medicine books in the treatment of myopia based on the data mining
Objective To explore the prescription and medication rules of ancient Chinese medicine books in the treatment of myopia based on data mining.Methods In the database of Chinese Medical Classic(5th edition)and Great Dictionary of Traditional Chinese Medicine Prescriptions,the terms"myopia""inability to see far""fear of distance vision""near vision"were searched.Microsoft Office Excel 2019 was used to establish a standardized prescription database,Origin 2022 was used to analyze the nature,flavour,and channel tropism,and Python 3.8.10 was used for association rule analysis,network analysis,and k-modes clustering analysis.Results A total of 45 prescriptions were included,including 85 traditional Chi-nese medicines.The efficacy of the prescription was mainly to nourish the liver and kidney and to nourish the heart and en-hance the intelligence.The frequency of drug efficacy was the highest for tonifying deficiency drug.The drug natures were mainly warm,slightly cold,cold,and flat.The drug flavours were mainly sweet,bitter,and pungent.The main channels were mainly liver,kidney,spleen,lung,and heart.There were 18 kinds of high frequency drugs,including Poria,Ginseng Radix Et Rhizoma,Polygalae Radix and so on.A total of eight drug combinations were obtained by drug association rule analysis.The 18 kinds,of high-frequency drugs were divided into three categories by clustering analysis of high-frequency drugs.Conclusion Ancient Chinese medical books mainly use nour-ishing the liver and kidney,nourishing the heart and enhancing the intelligence to treat myopia.The medication use is sweet,gentle and tonic without stagnation,which provides reference for myopia treatment.
MyopiaData miningPythonPrescription and medication rulesAncient Chinese medical books