Research progress on the effect of traditional Chinese medicine homolo-gous to food and medicine on the prevention and treatment of rheumatoid arthritis by regulating oxidative stress
In recent years,the incidence of rheumatoid arthritis has been increasing,showing a trend towards younger age groups,posing a serious threat to human health.Oxidative stress is a key mechanism in the pathogenesis of the disease and an important factor in its development.When joint cartilage is under high oxidative stress,it can easily induce cellular inflammatory reactions,leading to tissue damage and even extra-articular manifestations.Literatures review shows that traditional Chinese medicine homologous to food and medicine have a protective effect against oxidative stress damage in rheumatoid arthritis,and their effects are closely related to targets and related signaling pathways such as Nrf2,MAPK,PI3K,and NF-κB.Therefore,this article reviews the research progress on the prevention and treatment of oxidative stress in rheumatoid arthritis using eight medicinal and edible herbs with the same origin,in order to provide new ideas for clinical disease prevention and the development of functional food products.
Rheumatoid arthritisTraditional Chinese medicine homologous to food and medicineOxidative stressJoint synovitis inflammation