Diagnostic value of serum prealbumin combined with procalcition and C-reactive protein for infection after surgery for traumatic brain injury
Objective To explore the diagnostic value of serum prealbumin(PA),C-reactive protein(CRP),and procalcition(PCT)in patients with lung infection after surgery for traumatic brain injury.Methods A retrospective analysis was conducted on the clinical data of 80 postoperative patients with brain injury admitted to the Changzhou Medical District of the No.904 Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army from February 2017 to February 2022.They were divided into concurrent group(18 cases)and non concurrent group(62 cases)according to whether they have pulmonary infection.The basic data and serum levels of PA,CRP,and PCT were compared between the two groups.Logistic regression analysis was used to identify the influencing factors for postoperative pulmonary infection in patients with brain injury,and receiver operator characteristic(ROC)curve analysis was used to assess the diagnostic value.Results The proportion of concurrent group with a smoking of history,lung disease history,and the levels of CRP and PCT in the concurrent group were higher than those in the non concurrent group,while the serum PA was lower than that in the non concurrent group(P＜0.05);multiple logistic regression analysis showed that smoking(OR=4.651,95%CI= 1.829-11.822),history of lung disease(OR=4.791,95%CI:1.591-12.405),serum PA(OR=0.274,95%CI:0.097-0.776),serum PCT(OR=3.854,95%CI:1.665-0.916),and serum CRP(OR=4.671,95%CI:1.887-9.172)were all influencing factors for pulmonary infection in patients with traumatic brain injury(P＜0.05);the ROC analysis showed that serum PA,CRP,and PCT levels can be used to evaluate postoperative pulmonary infection in patients with traumatic brain injury.The areas under the curve were 0.943,0.920,and 0.817,respectively(P＜0.05).Conclusion The levels of serum PA,PCT,and CRP are closely related to pulmonary infection after surgery for traumatic brain injury,and the detection of these indicators can assist in evaluating the risk of pulmonary infection after surgery for traumatic brain injury.
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