Status and influencing factors of cancer-related fatigue in patients with bone tumor undergoing chemotherapy
Objective To investigate the status and influencing factors of cancer-related fatigue(CRF)in patients with bone tumor undergoing chemotherapy.Methods A total of 100 patients with bone tumor received chemotherapy in Beijing Jishuitan Hospital,Capital Medical University from February 2020 to January 2021 were selected,and assessed by revised Piper fatigue scale-Chinese version(RPFS-CV),social support rating scale(SSRS),and general self-efficacy scale(GSES).Patients were divided into CRF group(RPFS-CV score>three points,26 cases)and non-CRF group(RPFS-CV score≤three points,74 cases)according to the presence or absence of CRF.The clinical data of the two groups were compared,and the influencing factors of CRF were determined by multivariate logistic regression analysis.Results In this study,the total score of RPFS-CV in 100 patients with bone tumor chemotherapy was(4.54±1.02)points.The proportion of Ennecking stagesⅢ andⅣ,duration of disease,and frequency of chemotherapy in CRF group were higher than those in non-CRF group,and SSRS and GSES scores were lower than those in non-CRF group,the differences were statistically significant(P<0.05).Regression analysis showed that Ennecking stage(OR=1.485,95%CI:1.102-2.001),chemotherapy frequency(OR=2.307,95%CI:1.387-3.837),SSRS score(OR=0.319,95%CI:0.141-0.722),and GSES score(OR=0.512,95%CI:0.299-0.877)were the influencing factors of CRF(P<0.05).Conclusion Social support and self-efficacy can affect CRF in patients with bone tumor chemotherapy.Active intervention in social support and self-efficacy is conducive to reducing CRF in patients.
Bone tumorChemotherapyCancer-related fatigueSocial supportSelf-efficacyInfluencing factor