The dynamic balance of bone remodeling is the basis of normal tooth eruption.The signaling pathway regulating bone metabolism can precisely regulate this complex cascade process through the interaction of various cytokines.Autophagy is an important mechanism of cell self-protection.Recent studies have suggested a close relationship between bone remodeling and autophagy,but the specific mechanism of action is still unclear.This article reviewes the possible mechanisms of the interaction between major bone metabolic signaling pathways and autophagy in the formation of tooth eruption channels,aiming to provide a more comprehensive understanding of the molecular regulatory mechanisms,and biological properties of alveolar bone homeostasis during tooth eruption.
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