首页|非预期卵巢低反应患者的影响因素及个体化治疗的研究进展

非预期卵巢低反应患者的影响因素及个体化治疗的研究进展

Research progress on influencing factors of patients with unexpected poor ovarian response and individualized treatment

扫码查看
目前针对非预期卵巢低反应(POR)的治疗策略侧重于获取更多的卵母细胞,而波塞冬标准的提出至少获取 1 个可移植的整倍体胚胎,成为辅助生殖技术成功的新指标,因此将仅有的卵母细胞培育成优质胚胎是此类患者治疗的重要方面.本文重点阐述影响非预期POR的相关因素及其获取优质胚胎个体化治疗相关的 7 个措施:扳机日卵泡大小、双扳机方案、人工卵母细胞激活、囊胚移植、植入前非整倍体检测、时差成像、生物工程技术的应用.
Current treatment strategies for unexpected poor ovarian response(POR)focus on obtaining more oocytes,and the POSEIDON standard proposes to obtain at least one transplantable euploid embryo,it has become a new indicator of the success of assisted reproductive technology,so growing the only oocytes into high-quality embryos is an important aspect of the treatment of such patients.This paper focuses on the related factors affecting unexpected POR and seven measures related to obtaining high-quality embryo individualized treatment:trigger day follicle size,double trigger protocol,artificial oocyte activation,blastocyst transfer,preimplantation genetic testing for aneuploidy,time-lapse imaging,application of bioengineering techniques.

POSEIDONUnexpected poor ovarian responseEembryo qualityIndividualized treatment

马明男、朱霞、李慧珍、赵雨恒、黄炜瑜、马天仲

展开 >

广东医科大学附属医院生殖医学中心,广东湛江 524001

波塞冬标准 非预期卵巢低反应 胚胎质量 个体化治疗

广东省基础与应用基础研究自然科学基金项目

2022A1515010849

2024

中国医药导报
中国医学科学院

中国医药导报

CSTPCD
影响因子:1.759
ISSN:1673-7210
年,卷(期):2024.21(3)
  • 32