Application value of magnetic resonance imaging-diffusion weighted imaging combined with serum CYFRA211 in preoperative staging diagno-sis of rectal cancer
Objective To evaluate the application value of magnetic resonance imaging-diffusion weighted imaging(MRI-DWI)combined with serum CYFRA211 in preoperative staging diagnosis of rectal cancer.Methods The clinical data of 124 patients with rectal cancer admitted to Jiangyin Hospital Affiliated to Southeast University School of Medicine from January 2020 to April 2023 were retrospectively analyzed.Using pathological results as the gold standard,the diagnostic value of MRI-DWI combined with serum CYFRA211 in preoperative T and N stages of rectal cancer was analyzed.Results The pathological results showed that there were 16 cases of stage T1,14 cases of stage T2,46 cases of stage T3,and 48 cases of stage T4.There were 54 cases of stage N0,40 cases of stage N1,and 30 cases of stage N2.Serum CYFRA211 in patients with stage T4 was higher than that with stage T1,T2,and T3;serum CYFRA211 in patients with stage T3 was higher than that with stage T1 and T2,and serum CYFRA211 in patients with stage T2 was higher than that with stage T1(P＜0.05).Serum CYFRA211 in patients with stage N2 was higher than that with stage N0 and N1,and serum CYFRA211 in patients with stage N1 was higher than that in stage N0(P＜0.05).The area under the curve of preoperative diagnosis of stage T1,T2,T3,T4,N0,N1,and N2 of rectal cancer by serum CYFRA211 was 0.756,0.744,0.805,0.897,0.791,0.813,and 0.821,respectively.MRI-DWI was generally consistent in the preoperative diagnosis of stage T1,T2,T3,and T4(Kappa=0.452,0.587,0.672,0.720,P＜0.01);MRI-DWI combined with serum CYFRA211 showed good consistency in the preoperative diagnosis of stage T1,T2,T3,and T4(Kappa=0.768,0.785,0.827,0.839,P＜0.01).MRI-DWI was generally consistent in the preoperative diagnosis of stage N0,N1 and N2(Kappa=0.473,0.598,0.682,P＜0.01).MRI-DWI combined with serum CYFRA211 showed good consistency in preoperative diagnosis of stage N0,N1,and N2(Kappa=0.795,0.821,0.834,P＜0.01).Conclusion MRI-DWI combined with serum CYFRA211 has higher diagnostic value in preoperative stages T and N of rectal cancer.
Magnetic resonance imaging-diffusion weighted imagingCYFRA211Rectal cancerPreoperative staging
万方数据
维普
