Predictive value of fibrinogen/albumin ratio,Caprini score,and D-dimer for lower extremity deep venous thrombosis after acute cerebral infarction
Objective To investigate the predictive value of fibrinogen/albumin ratio(FAR),Caprini score,and D-dimer(D-D)for lower extremity deep vein thrombosis(LDVT)after acute cerebral infarction.Methods A total of 122 patients with acute cerebral infarction hospitalized in the Department of Neurology,Wuhu Traditional Chinese Medicine Hospital in Anhui Province from July 2019 to March 2023 were selected.According to the results of color Doppler ultrasound of both lower limbs during hospitalization,they were divided into thrombosis group(42 cases)and non-thrombosis group(80 cases).Basic data of the two groups were collected,the differences of FAR,Caprini score,D-D,and other indicators between the two groups were compared.The logistic regression model was established to analyze the influencing factors of LDVT formation after acute cerebral infarction,and the receiver operating curve was drawn to compare the predictive value of FAR,Caprini score,D-D alone and in combination for LDVT formation after acute cerebral infarction.Results The proportion of patients with diabetes mellitus,the proportion of patients with National Institutes of Health stroke scale score＞14 points,proportion of patients with Glasgow coma scale score＞8 points,the proportion of patients using dehydration drugs＞five days,Caprini score,D-D,and FAR levels in the thrombosis group were higher than those in the non-thrombosis group,and the differences were statistically significant(P＜0.05).Multivariate analysis showed that Caprini score(OR=1.803,95％CI:1.173-2.769),D-D(OR=1.589,95％CI:1.235-2.043),FAR(OR=1.609,95％CI:1.075-2.408)were the independent influencing factors of LDVT after acute cerebral infarction(P＜0.05).The area under the receiver operating curve of combined prediction of Caprini score,FAR,and D-D in predicting LDVT formation after acute cerebral infarction was higher than that of the three alone(P＜0.05).Conclusion FAR,Caprini score,and D-D are related to the formation of LDVT after acute cerebral infarction,and can be used as predictors of LDVT.Their combined detection can improve the predictive efficiency.
Cerebral infarctionLower extremity deep vein thrombosisFibrinogen/albumin ratioCaprini scoreD-dimer
万方数据
维普
