Effect of self-regulatory fatigue on chemotherapy tolerance in patients with multiple myeloma
Objective To investigate the status quo of self-regulatory fatigue in patients with multiple myeloma(MM)chemotherapy,and to analyze its effect on chemotherapy tolerance.Methods A total of 105 MM patients admitted to West China Hospital of Sichuan University from January 2020 to January 2022 were selected by convenient sampling method.Self-regulated fatigue scale(SRF-S),cancer experience and efficacy scale(CEES)and cancer patient self-management assessment scale were used to evaluate patients'self-fatigue and cancer self-management.The chemotherapy tolerance of MM patients and the effect of self-regulating fatigue on chemotherapy tolerance of MM patients were observed and analyzed.Results A total of 105 MM patients were included in this study.A total of 105 questionnaires were sent out,and 100 were effectively recovered,with an effective recovery rate of 95.24%.The SRF-S score of 100 MM patients was(53.28±11.14)points.The cancer experience score of CEES was(46.63±12.82)points,and the control efficacy score was(35.47±7.51)points.The average self-management score was(157.54±20.93)points.The SRF-S score of poor chemotherapy tolerance group was higher than that of good chemotherapy tolerance group,and the difference was statistically significant(P<0.05).By point two-column correlation test,SRF-S score was positively correlated with chemotherapy tolerance of MM patients(r>0,P<0.01).Conclusion There is a significant correlation between self-regulated fatigue and chemotherapy tolerance in MM patients.Nursing staff can implement effective intervention according to patients'self-regulated fatigue status to improve chemotherapy tolerance.
Multiple myelomaChemotherapyChemotherapy toleranceSelf-regulation fatigueCancer experience and efficacySelf management