Objective To explore the rules of medicinal use of Chinese medicine in the intervention of vessel bi based on the national patent compound prescription.Methods The national patent database was searched by computer from inception to March 2023 on the patent compound prescription of traditional Chinese medicine intervention in vessel bi.Excel was used for data cleaning and statistics of frequency,nature and flavour,channel tropism.SPSS Modeler 18.0 and R.4.3.1 were used for traditional Chinese medicine correlation and hierarchical cluster analysis.Cytoscape 3.9.1 visually upgrade the co-occurring network.Results In this study,124 patent compound prescriptions were included,involving 324 kinds of traditional Chinese medicine.The high frequency Chinese medicine included Salviae Miltiorrhizae Radix Et Rhizoma,Astragali Radix,and so on.The drug natures were mainly cold and warm,and the drug flavours were mostly bitter,sweet,and pungent,and the main channel tropism was liver channel.Common drug pairs included"Astragali Radix and Salviae Miltiorrhizae Radix Et Rhizoma"and so on.Commonly used three drug combination included"Crataegi Fructus-Salviae Miltiorrhizae Radix Et Rhizoma-Chuanxiong Rhizoma"and so on.The hierarchical clustering resulted in four cluster combinations.Conclusion The patented compound prescription is mainly used to promote blood circulation and remove blood stasis,reduce turbidity and lipids,and supplement qi and blood.This study sorted out the core traditional Chinese medicine for the treatment of vessel bi,in order to provide ideas for clinical potential prescription medicine and future new drug research and development.
维普
万方数据