Construction and evaluation of animal model of common spleen and stomach diseases based on combination of disease and syndrome
Animal experiments are of great significance in promoting the research and development of new drugs and clarifying pharmacological mechanisms.With the modernization of traditional Chinese medicine,animal experiments combining disease,and syndrome have been widely used by more and more scholars,and the construction and evaluation system of animal models have been gradually improved.the spleen and stomach diseases have a high incidence and are not easy to be cured.Traditional Chinese medicine has unique advantages in the treatment of spleen and stomach diseases.In order to further study the molecular mechanism and efficacy of traditional Chinese medicine in the treatment of spleen and stomach diseases,it is of great significance to prepare the relevant disease-syndrome combined animal model.The simple Western medicine disease model has some limitations,and the combination of disease and syndrome with animal model is in line with traditional Chinese medicine syndrome differentiation and treatment,which is particularly important for the pathogenesis of spleen and stomach diseases and the development of new drugs.Therefore,the author summarized the construction method and evaluation system of the common spleen and stomach diseases combined with each syndrome of animal model,and expounded the development and establishment characteristics of the combined animal model of spleen and stomach diseases,so as to solve the key problems of the evaluation indicators of the disease of animal experimental model,improve the disease modeling and measurement standards,and provide reference for researchers,promote the further development of traditional Chinese medicine treatment of spleen and stomach diseases.
Combination of disease and syndromeAnimal modelsSpleen and stomach diseasesExperimentEvaluation system constructionTraditional Chinese medicine
万方数据
维普
