Study on the correlation between visceral fat area and subclinical hy-pothyroidism in patients with type 2 diabetic mellitus
Objective To analyze the relationship between subclinical hypothyroidism(SCH)and visceral fat area(VFA)in patients with type 2 diabetes mellitus(T2DM).Methods A total of 559 patients with T2DM hospitalized in the Department of Endocrinology,the First Hospital of Lanzhou University from July 2021 to September 2022 were selected and divided into T2DM combined SCH group(75 cases)and T2DM alone group(484 cases)according to their thyroid stimulating hormone levels.The differences of serum total cholesterol(TC),triglyceride(TG),high density lipoprotein-cholesterol(HDL-C),low density lipoprotein-cholesterol(LDL-C),dyslipixia rate,body mass index(BMI),VFA,subcutaneous fat area(SFA),VFA/SFA,fat percentage of Android region(A),fat percentage of Gynoid region(G),A/G,trunk fat percentage(TF%),and body fat percentage(BF%)were compared between the two groups.The influencing factors of T2DM combined SCH were analyzed by binary logistic regression model.Results The female proportion,TC,LDL-C,VFA,A,G,TF%,and BF%in T2DM combined SCH group were higher than those in T2DM alone group,and the differences were statistically significant(P<0.05).Binary logistic regression model analysis showed that VFA was an independent risk factor for T2DM combined with SCH after adjusting for confounding factors(OR>1,P<0.05).Conclusion VFA level is increased in T2DM patients with SCH,which has a certain causal relationship with the incidence of SCH in T2DM patients.
Type 2 diabetes mellitusThyroid stimulating hormoneVisceral fat areaSubclinical hypothyroidism