Diagnostic value of ankle-brachial index combined with serum 25-hydro-xyvitamin D level in lower extremity vascular lesions of type 2 diabetes mellitus
Objective To investigate the diagnostic value of ankle-brachial index(ABI)combined with serum 25-hydroxy-vitamin D(25[OH]D)level in lower extremity vascular lesions of type 2 diabetes mellitus.Methods A total of 179 patients with type 2 diabetes mellitus admitted to Bozhou People's Hospital in Anhui Province from July 2018 to January 2021 were selected and divided into non-lesion group(106 cases)and lesion group(73 cases)according to whether they had lower extremity vascular lesions.The influencing factors of lower extremity vascular lesions in patients with type 2 diabetes mellitus and the diagnostic value of ABI-combined with serum 25(OH)D levels were analyzed.Results The age,glycosylated hemoglobin,and lowdensity lipoprotein-cholesterol in the lesion group were higher than those in the non-lesion group,and the albumin,ABI,and serum 25(OH)D levels were lower than those in the non-lesion group(P＜0.05).Multivariate analysis showed that age(OR=2.843,95％CI:1.250-6.468),glycosylated hemoglobin(OR=3.056,95％CI:1.343-6.951),ABI(OR=2.724,95％CI:1.197-6.196),and serum 25(OH)D level(OR=3.979,95％CI:1.749-9.051)were the influencing factors of lower extremity vascular lesions in patients with type 2 diabetes mellitus(P＜0.05).The area under the curve of the combination of ABI and serum 25(OH)D level in predicting lower extremity vascular lesions of type 2 diabetes mellitus was higher than that of ABI and serum 25(OH)D level alone(P＜0.05).Conclusion ABI combined with serum 25(OH)D level has a certain diagnostic value for lower extremity vascular lesions in patients with type 2 diabetes mellitus,which should be paid attention to in clinical practice.
万方数据
维普
