首页|外周血炎症指标淋巴细胞/单核细胞比值、平均血小板体积及血小板分布宽度在HELLP综合征中的预测价值

外周血炎症指标淋巴细胞/单核细胞比值、平均血小板体积及血小板分布宽度在HELLP综合征中的预测价值

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目的 探讨外周血炎症指标淋巴细胞/单核细胞比值(LMR)、平均血小板体积(MPV)及血小板分布宽度(PDW)在HELLP综合征中的预测价值.方法 选取2021年1月至2022年12月河北省沧州市人民医院收治的重度子痫前期患者160例,根据是否并发HELLP综合征将其分为HELLP组(42例)和非HELLP组(118例),收集并比较两组临床资料;分析HELLP综合征发生的危险因素及LMR、MPV及PDW对HELLP综合征的预测价值.结果 HELLP组白细胞计数、中性粒细胞计数、LMR、MPV及PDW高于非HELLP组,差异有统计学意义(P<0.05).LMR、MPV、PDW 是 HELLP综合征发生的危险因素(OR=1.701、1.894、1.593,P<0.05).LMR、MPV、PDW 联合预测HELLP综合征的曲线下面积高于各指标单独检测(P<0.05).结论 LMR、MPV及PDW是HELLP综合征发生的危险因素,三者联合对HELLP综合征发生有一定的预测价值,早期预测有助于正确处理和采取必要的预防措施.
Predictive value of peripheral blood inflammatory indicators lymphocytes/monocytes ratio,mean platelet volume,and platelet distribution width in HELLP syndrome
Objective To investigate the predictive value of peripheral blood inflammatory indicators lymphocytes/mono-cytes ratio(LMR),mean platelet volume(MPV),and platelet distribution width(PDW)in HELLP syndrome.Methods A to-tal of 160 patients of severe preeclampsia who were admitted to Cangzhou People's Hospital of Hebei Province from January 2021 to December 2022 were enrolled.They were divided into HELLP group(42 cases)and non-HELLP group(118 cases)according to whether or not complicated with HELLP syndrome.The clinical data of two groups were collected and com-pared;the risk factors of HELLP syndrome were analyzed;the predictive value of LMR、MPV,and PDW in HELLP syn-drome were analyzed.Results White blood cell count,neutrophil count,LMR,MPV,and PDW in HELLP group were higher than those in non-HELLP group,and the differences were statistically significant(P<0.05).LMR,MPV,and PDW were the risk factors for HELLP syndrome(OR=1.701,1.894,1.593,P<0.05).The area under the curve of LMR,MPV,and PDW combined detection was higher than that of single detection(P<0.05).Conclusion LMR,MPV,and PDW are the risk factors for HELLP syndrome.The combination of LMR,MPV,and PDW can predict the occurrence of HELLP syndrome.Early prediction is helpful to correct treatment and take necessary preventive measures.

HELLP syndromeLymphocytes/monocytes ratioMean platelet volumePlatelet distribution width

门贺伟、刘倩、李霞、谢晓梅、王丽丽

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河北省沧州市人民医院妇产科,河北沧州 061000

HELLP综合征 淋巴细胞/单核细胞比值 平均血小板体积 血小板分布宽度

河北省医学科学研究课题计划项目

20210432

2024

中国医药导报
中国医学科学院

中国医药导报

CSTPCD
影响因子:1.759
ISSN:1673-7210
年,卷(期):2024.21(6)
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