Analysis on the medication rules of traditional Chinese medicine in treat-ing acne by famous Chinese doctor in capital of China Qian Wenyan
Objective To summarize the medication rules of Qian Wenyan,a famous Chinese doctor in capital of China,in treating acne by using data mining technology.Methods Prescriptions for dermatology outpatient department of Professor Qian Wenyan from China-Japan Friendship Hospital from January 2014 to December 2022 were collected.After data screening and sorting,frequency analysis,association rules,and K-means cluster analysis were used to explore and discuss prescription drug frequency,nature and flavour,channel tropism,efficacy,core combination,etc.Results A total of 301 prescriptions were collected,involving 170 kinds of traditional Chinese medicine,with a cumulative frequency of 4 690,29 kinds of high-frequency drugs(frequency≥40).The drug natures of high-frequency drugs were mainly cold,the drug flavours were mainly bitter,sweet,and pungent,mainly belongs to liver and lung channels,and the efficacy of heat-clearing drugs was the most.Association rule analysis showed that the core drug combination was"Lonicerae Japonicae Flos-Forsythiae Fructus-Scutellariae Radix-Paeoniae Radix Rubra-Taraxaci Herba",and the three new prescriptions were obtained by K-means clustering.Conclusion By using data mining technology,this paper summarizes the rules of medicine used by Professor Qian Wenyan to treat acne.In clinical treatment,Professor Qian Wenyan uses cold and bitter drugs,mainly into liver and lung channels.Clinical treatment focuses on clearing heat and removing fire,removing dampness and removing blood stasis,and the clinical effect is quite good.